A member asked:

Can depoprovera be the cause of cramps in my legs?

A doctor has provided 1 answer
Dr. Lee Ann Roberts answered

Specializes in Gynecology

Possible,not typical: Estrogen is the usual hormonal cause of leg cramps, but there can be other nonhormonal causes as well. Estrogen is not present in depoprovera as it is a progesterone-only method. Leg cramps are listed in the pdr as an infrequent side effect of depoprovera, but in the experience of most gynecologists their patients on depoprovera rarely have that complaint.

Answered 10/16/2017

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