Is passing tissue 1st time on depo while 2 weeks on menstrual cycle normal ? and is there medicine to stop the bleeding?

Be patient: For the first couple months after starting Depo Provera, (medroxyprogesterone) you may continue to have a light period, even breaking through at two weeks. After time the lining of the uterus thins and bleeds less and less, resulting in very light or no periods.

See answer:: Excessive vaginal bleeding is common on Depo-Provera. This tends to subside with continued use. Passing tissue would not be an effect of the medication, but if you're bleeding heavily you may have larger blood clots looking like tissue. Estrogen pills or transdermal patch may help stop excessive bleeding. Consult your Dr. SEE:http://abt.cm/1Is7lzm