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A member asked:
I have herpes simplex type 1 ( cold sores ) not responding to acyclovir is there an alternative ?
A doctor has provided 1 answer
See a dermatologist: Acyclovir is effective orally, not topically. Must be used at prodrome or daily to be effective. Your dose may be too small. Valacyclovir is much more effective, used at 2 gram dose at prodrome: as soon as you feel the first tingling. Repeat once in 12 hours. Chapstick with sunscreen helps reduce frequency. Lysine is useless. Topicals do very little.
Answered 12/21/2014
3.4k views
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