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A 43-year-old member asked:

What sex is someone with klinefelters?

1 doctor answer6 doctors weighed in
Dr. Henry Ng
Dr. Henry Nganswered
Internal Medicine and Pediatrics 20 years experience
Genetic male: A person with kleinfelter's syndrome has three sex chromosomes, XXY instead of the typical two, xy. The presence of the y chromosome makes them a genetic male.
Dr. Martin Raff
Dr. Martin Raff commented
Infectious Disease 56 years experience
There are many variances within the XXY population, just as within the 46,XY population. While it is possible to characterise XXY males with certain body types and physical characteristics, that in itself should not be the method of identification as to whether or not someone has XXY. The only reliable method of identification is karyotype testing. The degree to which XXY males are affected, both physically and developmentally, differs widely from person to person.
Mar 7, 2013

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