Headaches, acid reflux, fatigue and muscle aches. are these symptoms due to my 3 month lupron (leuprolide) depot injection?

Maybe: All these are symptoms that patients complain on Depo-Provera Lupron (leuprolide) but have not been substantiated by the company. My experience is that when you take hormone replacement back they get better. Ask your md if you could have add-back therapy, although typically this is done after 6 mo of Depo-Provera Lupron (leuprolide) for endometriosis or cancer.