What's mechanism of action of isoniazid in cerebellar ataxia in multiple sclerosis?

None?: There was mention of some research articles about 30 years ago... Looked like Isoniazid did not have an effect, or if it did, the number of patients studied was much too small for the researchers to say any noticeable changes were due to isoniazid. An article (http://www.Ncbi.Nlm.Nih.Gov/pmc/articles/pmc3105633/) mentions koller 1984, bozek et al. 1987, francis et al. 1986, and sabra et al. 1982.

Tough to treat: Cerebellar ataxia is a tough problem too control, but Isoniazid is not going to help. In fact, the only drug that has ever seemed useful symptomatically was buspar, and it helped only a small percentage. Better, if you have ms is to immediately treat all relapses, and use a potent disease modifying agent, such as tysabri, (natalizumab) gilenya, or tecfidera, as there is a chance that some problems may reverse.