A member asked:

Can benedryl be taken if you have high blood pressure?

3 doctors weighed in across 3 answers

It depends: Benadryl (diphenhydramine) by itself can be used with people with hypertension with caution on short period of time, if combined with decongestants, then, no.

Answered 6/24/2014

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Yes : Antihistamines don't affect blood pressure. Don't take medicines that say "d" or contain pseudophedrine in addition to the benadryl (diphenhydramine).

Answered 1/11/2017

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Dr. Payam Mehranpour answered

Specializes in Internal Medicine - Cardiology

Yes: Benadryl (diphenhydramine) does not have adverse effect on blood pressure or significant interaction with hydrochlorothiazide.

Answered 9/14/2015

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