Bertolotti's Syn-: drome is a congenital anomaly of the lower lumbar vertebrae & a cause of back pain in children, teens & adults. I could find no specific genetic mutation known to be the cause.
Answered 10/31/2014
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Bertolotti’s syndrome is intervertebral disc degeneration above the level of a lumbosacral transitional segment. The degeneration often takes the form of a disc herniation and results in spinal canal stenosis and potentially effacement of spinal nerves. The transitional anatomy is a developmental anomaly or variant of normal anatomy. However, it is not a genetic syndrome.
Answered 3/9/2021
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