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A 36-year-old male asked:

Mechanisms of action of keppra (levetiracetam)?

2 doctor answers4 doctors weighed in
Dr. Robert Kent
Physical Medicine and Rehabilitation 12 years experience
Not completely known: However, it is hypothesized that it binds to a pre-synaptic glycoprotein that inhibits calcium channels affecting conduction across the synapse. Hope this answers your question and best of luck!
Dr. Donald Jacobson
A Verified Doctoranswered
A US doctor answeredLearn more
Not known: The best info i could find on this is on the wikipedia.Com website and reads as follows : the exact mechanism by which Levetiracetam acts to treat epilepsy is unknown. However, the drug binds to a synaptic vesicle glycoprotein, sv2a, [26] and inhibits presynaptic calcium channels.[27] this is believed to impede impulse conduction across synapses.[28].

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Last updated May 20, 2015

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