Can you die from gallbladder disease?

Very rare.: Gallstones can cause infection which could result in septic shock. Usually that could be treated with antibiotics and surgery. Cancer of the gallbladder or bile ducts is very rare. Symptomatic gallbladder disease requires attention.

Yes: The three main complications from gall bladder disease are: acute cholecystitis, pancreatitis and obstructive jaundice. These conditions can lead to serious complications including death. That is why, if you have symptoms attributable to gall stone disease, you should consult a surgeon about having your gb removed electively.