My opinion: No: Zoloft (sertraline) can cause a creepy crawly feeling or twitching in the arms and/or legs. This is thought to be due to spillover into dopaminergic neurons especially at the higher doses. It can be calmed down with klonopin, but you need to review the pro's and con's of having abnormal muscle movements with your treating physician.
Answered 8/10/2013
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