Having pcod. doc advice to take metformin 2gms, l-arginine, myo-inositol, folate, (folic acid) vit d3 (3 months). still irregular periods. pls advise.

Reasonable: That regimen for pcos is reasonable. It may take longer for metformin to regulate periods. The addition of spironolactone, a pottasium sparing diuretic has been shown to increase the success at regulating periods in pcos. It also serves the dual function of decreasing water retention and blocking testosterone effect at the hair follicle, decreasing the hirsutism that can occur with pcos.