Can: Topomax (topiramate) may decrease the serum concentration of contraceptives (estrogens) and contraceptive failure is possible, particularly at higher topiramate doses (i.e., 200mg/day or greater). At 100 mg of topmax, recommend at least 50 mcg of ethinyl estradiol. A non-hormonal form of contraception should be considered if a greater certainty of pregnancy prevention is desired.
Answered 10/24/2017
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