Is dhea in a feedback loop?

While ACTH: Can stimulate dhea production, the exact mechanism of dhea regulation is unknown. Beware of junk you read on the internet re: dhea and it's significance in medical disease or use as a therapy. It is metabolized to estrogen, testosterone or cortisone -- and you can't control which it's converted into. Stay away from dhea supplements, most don't have much active ingredient anyway.