A member asked:

My 42 yr old fiance is on zoloft (sertraline) 100mg a day our sexual activitie is limited, can zoloft (sertraline) affect he's libido, and if so how much?

5 doctors weighed in across 2 answers

Sure can: Zoloft (sertraline) makes part of the group of medications known as ssris (selective serotonin reuptake inhibitors). One of the side effects is decreased libido. All of the antidepressants except for bupropion (brand name wellbutrin) are known to mess up with that.

Answered 7/13/2013

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Yes: Yes, zoloft (sertraline) can have a significant impact on sex drive & can impact ability to ejaculate& to sustain an erection. It can cause impotence.

Answered 7/13/2013

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