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A member asked:
Can you please tell me why excessive quantities of mdma or ecstasy cause derealization and depersonalization?
4 doctors weighed in across 2 answers
Mdma: Also known as ecstasy, it causes elevation of brain adrenaline, Dopamine & serotonin, leading to feelings of increased energy, euphoria, empathy towards others, emotional warmth, sexual arousal & distortion of sensory/time perceptions.
Answered 6/25/2014
4.9k views
MDMA: Mdma is a hallucinogen which mixes amphetamine and mescaline-type effects. It impacts serotonin, dopamine, and norepinephrine -- the serotonin effects may be responsible for the known pro-social effects of the drug. It causes release of oxytocin and vasopressin, which play strong roles in love, trust, and sexual feelings. Dopamine activity can lead to depersonalization/derealization.
Answered 1/13/2016
4.9k views
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