Fluid retention: None of the common antihypertensives is associated with significant weight gain. However, even placebo causes weight gain. So, a certain percentage of people who take antihypertensives will gain weight and think it is due to medication. Calcium channel blockers (amlodipine, nifedipine, etc) as a group may cause peripheral edema / mild weight gain but this is simply fluid, easily dealt with.
Answered 4/11/2019
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