Arteriosclerosis: Arteriosclerosis is a hardening of the arteries. This happens from fat, cholesterol or other harmful substances stick to the wall of the artery and form a plaque. Over time, the plaque can grow and end up closing off most of the artery. This causes a decreased blood flow and you can get problems with the extremities from them not getting enough blood.
Answered 11/9/2015
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Similar process: Progressive injury to the vascular wall of blood vessels feeding different tissues is the the process. The symptoms arise from compromise of the affected organ or tissue. In the extremeties, one can experience pain and cramping with use or exercise. If severe, gangrene can develop, possibly prompting amputation. Sort out risk factors and consult your healthcare provider to intervene.
Answered 11/6/2014
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