A member asked:

I'm on amitriptyline, pregabalin and methadone. i have severe mood swings, which is the cause if any?

A doctor has provided 1 answer
Dr. William Newton answered

Specializes in Pain Management

They all can: Amitriptyline and Pregabalin are medications that come from classes of medications that can be used to treat depression and mood disorders as well as pain. I would put more emphasis on these rather than the methadone. All in combination can be your issue.

Answered 6/30/2014

5.1k views

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