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A member asked:
I was prescribed minocycline capsules for my acne. can i break the capsule & apply it topically by mixing it with my clindamycin cream?
A doctor has provided 1 answer
No: Tetracyclines reach the deeper structures via the bloodstream; it's part why they're best as a systemic medication. They also control new infections before they form. There's a bunch of studies that pretty much showed topical tetracycline isn't very effective, not nearly as good as the clindamycin.
Answered 5/16/2013
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