Not usually: This is a brand new medicine on the market for relapsing-remitting ms, and has yet to be widely employed. So far, main issues involve flushing, nausea, diarrhea, stomach upset, and low lymphocyte count. 4 cases of pml are described in fumaderm which has half the dose of dimethyl fumarate, but not clear if tecfidera might cause pml also. But depression not a side effect.
Answered 12/15/2015
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