A member asked:

Why is the glycosylation of dystroglycan important for its function as in the case with duchennes muscular dystrophy?

A doctor has provided 1 answer

Muscle unstable: Dystrophin is an important components of the skeleton of the muscle fiber that helps keep the membrane stable and the membrane proteins "anchored" in the correct place in the cells that allows to perform their normal function. When this is absent such as in duchenne, the muscle fibers degenerate. The sarcoglycans are other components that are linked to dystrophin and have relatively similar role.

Answered 10/23/2013

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