What are your thoughts? could you always experience side effects when doing chemo?

Never say always: We do not like to say always to anything (except that it's always good to be healthy). Side effects depend on the specific chemo, general health, concurrent medications, and the capacity of the person to metabolize said chemo. Expect some side effects but be optimistic. Also, make sure the benefits of any treatment justify the side effects and potential loss of quality of life. Best to you.