Nyquil has acetaminophen, dextromethorphan (cough suppressant) and doxylamine an antihistamine Antihistamines make on cause drowsiness and Flexeril makes one very drowsy (what dose- 5 or 10 mg? ) so I would not take them together. Space them 4 hours -8 hours apart at least , as Flexeril is very sedating.
Answered 1/31/2023
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