If you had chaffing between you thighs and it turned into a wound what should you do?

Keep the area clean with an antibacterial soap and cover the area with a thin layer of antibiotic cream. When possible, air out the area. Soft cotton clothing may not aggravate the area as much as other fabrics. If this does not help, see your doc.

Agree with Dr. Ferguson. You also need to address the cause of chaffing. If it is due to being overweight and your thighs rubbing together, losing weight would be imperative.