A member asked:

Im on combination tri sprintec lo birth control and on amoxicillin 875 mg right now. my period is over but im spotting while on active pills. can the antibiotic cause this? it has a label on the bottle about effectiveness

A doctor has provided 1 answer

Wouldn't think so: Amoxicillin and other commonly used antibiotics do not have a noticeable effect on the workings of hormonal contraceptives such as combination birth control pills. The antibiotic Rifampin is not commonly used, but can have an effect on hormonal contraceptives.

Answered 5/2/2020

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