A member asked:

Been on 40mg of protonix twice a day & 20mg pepcid twice a day for weeks, once rx is done, is there any kind of symptoms thatll happen after abruptly stopping? on the medicine for gastritis, esphogitis & peptic ulcer, having gallbladder surgery tues

A doctor has provided 1 answer

Rebound Acid product: It is important to administer PPIs only for patients who will gain a substantial clinical benefit . Beneficial effects of PPIs for GERD and prevention of NSAID-induced ulcers are strong enough when given to appropiate patients. Studies shows best evidence yet that withdrawal from PPI therapy is associated with a clinically meaningful increase in Acid production , above pre treatmend level.

Answered 4/24/2023

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