I have a headache, what i need to be?

Depends on details: Most people get a headache at some time, such as from colds, infections, lack of sleep, too much driving, long hours on the computer, stress at work, etc. Over-the-counter drug options include Tylenol (acetaminophen), Motrin, Aleve, Excedrin Migraine, and their generic brands. A bad or increasing headache, recurrent headache, weird headache or one with other worrisome symptoms should be examined.