I need the best medication for chronic constipation, tried movicol and dulcolax, they are not helping.

No other disease?: Each person with constipation needs to be sure there is no other disease causing it. If constipation is just due to slow movement of the food and poop through the gut, then the things to try are vegetables, water, prune juice, prunes, fiber plus water, Miralax (polyethylene glycol) Senokot or other senna, milk of magnesia, etc... A doctor can evaluate, and might prescribe Amitiza or Linzess.