A member asked:

Hi is there a difference regarding adderall in the medication amphetamine dextroamphetamine and amphetamine salts combo? i felt different on each.

3 doctors weighed in across 2 answers
Dr. Robert Zagar answered

Specializes in Adolescent Medicine

Caffeine is safer: Adderall, dextroamphetamine amphetamine have significant side effects. A University of Minnesota Psychiatry Professor who developed the Test of Variable Attention, a sensitive specific measure of hyperactivity & attention deficit once commented that caffeine will give 1/2 the dose of ritalin. I start with caffeine and move to medications later.

Answered 8/26/2017

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Dr. Daniel Ziegler answered

Specializes in Emergency Medicine

Subtle difference: Drugs & molecules occur in 2 forms with the same composition called enantiomers & are physical mirror images: dextro (right), levo (left). Racemic is a mixture of both. Biologic systems use d versions almost exclusively and d-amphetamine is generally more active than l-amphetamine. Amphetamine is racemic amphetamine with d:l ratio of 1:1. The "salts" (Adderall) work out to be a 3:1 ratio

Answered 10/23/2017

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