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A 38-year-old female asked:

My dr has me on low dose methotrexate, tramadol, wellbutrin xr, buspar, (buspirone) xanax and ambien. are all these drugs safe together?

1 doctor answer1 doctor weighed in
Dr. Bennett Machanic
Neurology 54 years experience
Comments: I would not be surprised to encounter drug-drug interactions here, which could enhance adverse effects, and even compromise intended efficacy. Not having a clue as to why you take any of these, I cannot advise further, but think you would do well to have an extensive discussion with your doctor about all of this.
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Last updated May 14, 2021


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