Resistant bp stays at 160/80 despite micardis 20, bystolic (nebivolol) 10. norvasc 5-10 mg works but get leg edema. imdur raises bp to 180. diuretics? ckd patient

Diuretics for HTN: Hypertension which is not uncontrolled on 2 drugs often needs a diuretic. There is sometimes fear that diuretics will worsen kidney function, but in fact BP control is especially important for patients with kidney disease. A very low salt diet will help. See "Loop Diuretics are Most Appropriate for Hypertension Treatment in Chronic Kidney Disease" J Am Soc Hypertension 2016.