What are indications for amniocentesis?

Intra uterine diagno: Multiple indications for amniocentesis exist. The most common use of amniocentesis is to diagnose fetal chromosomal anomalies after other tests such as ultrasound or biophysical markers have determined a significant likelihood that the fetus will be affected with a chromosomal problem. Other diagnostic tests performed using amniocentesis are determining fetal lung maturity and evaluating alloimmunization. Amniocentesis can also be used to obtain samples to rule out chorioamnionitis in cases in which the clinical picture is unclear, as well as to deliver intra-amniotic dye in cases in which premature rupture of membranes is suspected.[2, 3, 4, 5] Therapeutic indications for an amniocentesis may include the direct delivery of medications to the unborn fetus and to release intrauterine pressure in the presence of polyhydramnios.