A member asked:

Hi, i've been on 50 mg of zoloft for 11 days. i take it in the morning per my prescribing physicians instructions. it makes me very tired about 30 min after taking it, where i can't function. the drowsiness lifts about 4 hours later. is this a side effect

3 doctors weighed in across 2 answers

Zoloft (sertraline): Yes, it could be a side effect. I would suggest speaking with the prescribing physician of taking it at night.

Answered 5/15/2016

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Dr. Robert Olsen answered

Specializes in Psychiatry

Yes it likely is.: Sedation is a less common side effect but occurs in 13-15% of patients; it may or may not resolve over time. Zoloft (sertraline) has a 26 hour half life, so it doesn't matter what time you take the medication it will stay in your system and not washout over the course of the day or the night for that matter. Talk to your doctor about this somnolence and get his/her recommendations.

Answered 11/11/2015

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