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A 44-year-old male asked:

is it possible wellbutrin (bupropion) is causing me to feel symptoms of peripheral neuropathy? i

2 doctor answers3 doctors weighed in
Dr. John Moranville
Psychiatry 36 years experience
Unlikely: antidepressants are often used for treating the pain associated with peripheral neuropathy. Though Wellbutrin is unlikely to help as far as I know there have been no reports of it exacerbating or causing neuropathy. TCAs such as nortriptyline or amitriptyline and SNRIs like venlafaxine (Effexor) and Cymbalta (duloxetine) have been shown to decrease neuropathic pain
Dr. Bennett Machanic
Neurology 52 years experience
Unlikely: Wellbutrin (bupropion) would be an unusual cause for peripheral neuropathy and would search for a different explanation, at least initially. Reports of nerve toxicity in the PDR are often based on coincidental association, and do not always represent cause and effect.

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Last updated May 16, 2016
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