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Houma, LA
A 20-year-old male asked:

I take kristalose/lactulose daily. can this cause lactic or metabolic acidosis? are there any recommendations for monitoring?

1 doctor answer2 doctors weighed in
Dr. Richard Roberts
Pediatrics 46 years experience
No, It is inert: Kristalose, a brand of lactulose, is an indigestible disaccharide for treating constipation. It arrives intact in the large bowel. Bacteria break it down to lactic and formic acid increasing osmotic pressure, drawing in water, softening stool in one to two days due to transit time to the colon. Antacids may inhibit it's effect. In the elderly, it may disrupt electrolyte balance in six months.
Dr. Richard Roberts
Pediatrics 46 years experience
Provided original answer
A better question to ask – why is a 20-year-old chronically constipated? you need a clinical evaluation to determine the cause and not concentrate on a treatment. You may require a gastroenterologist referral. For acute constipation I personally recommend trying a bag of cherries--plus adequate hydration
Sep 13, 2015

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Last updated Feb 24, 2018
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