Had a 32oz margarita at 4pm ct is it ok to take a .25mg xanax (alprazolam)? prescribed it for anxiety

Depends: Average male processes approximately 1 standard drink per hour, so it depends on the # of standard shots in a margarita and how long you were drinking. In wanting to avoid mixing alcohol with benzodiazepines, an important question: when was Xanax (alprazolam) last taken prior to drinking and how often? Half life is typically 11-12 hours, and can remain in your system for 2-3 days or longer with regular use.