A member asked:

On second depo shot can it make your boobs hurt? be sore can it also darken your nipples?

A doctor has provided 1 answer
Dr. Christopher Plummer answered

Specializes in Maternal-Fetal Medicine

Yes: The progesterone is a pregnancy hormone that is made in large quantity when you are pregnant. It can cause nipple tenderness and may cause darkening of the nipple and areola, just like in pregnancy. Using depo-provera give long term dose of progesterone to prevent you from getting pregnant for 12 weeks. So this is not uncommon, Good luck!

Answered 11/28/2017

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