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A 23-year-old female asked:
Can i take 5mg of ambien (zolpidem) and fioricet (without codeine) together?
2 doctor answers • 2 doctors weighed in

Dr. Bennett Machanicanswered
Neurology 54 years experience
Risky combination: Fioricet is a barbiturate, and large doses can interfere with breathing. Ambien (zolpidem) plus Fioricet causes marked drowsiness. Putting all together, you could sleep so soundly that there could be risk of aspiration, but if you have any sleep apnea, respiratory drive might be substantially suppressed. Discuss this with your doctor.
Created for people with ongoing healthcare needs but benefits everyone.
5.2k viewsReviewed >2 years ago

Dr. Heidi Fowleranswered
Psychiatry 27 years experience
Drug interactions.: Agree with Dr. Machanic. That medication combination may cause dizziness, drowsiness, confusion, & difficulty concentrating (per the Drugs.Com drug interaction checker). The fioricet contains a barbiturate.
Created for people with ongoing healthcare needs but benefits everyone.
7 viewsAnswered >2 years ago
Last updated Jan 30, 2021
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