Can lasix (furosemide) and metalazone be taken at the same time?

Diuretics: Yes, but the combination can result in an extreme loss of potassium so that electrolyte needs to be closely monitored. That combination is used sometimes in patients with extreme refractory heart failure with severe fluid retention. It is probably dangerous to take the combination in individuals without such problems. Extreme loss of potassium may result in life threatening arrhythmias.

Diuretic combo: Yes, both can be taken at the same time. Lasix (furosemide) is a loop diuretic and can be used in combination with Metolazone to deliver a greater diuresis than Lasix (furosemide) gives by its self. You should have your doctor test the patient for other causes of leg edema, such as varicose veins or pulmonary artery hypertension to make sure the edema is being treated appropriately, good luck.