A member asked:

What is the meaning of: hepatitis c antibody reactive with sgnal to cut-off: 34.00?

3 doctors weighed in across 2 answers

(+) test for Hep C: This means the body has had exposure to hep c and the immune system now remembers to fight the infection and has memory cells that carry antibodies against hep c. It may mean active infection as 75% are not able to clear the infection completely or past infxn if you are 1 of lucky 25% that kills all the virus at first encounter. The cut off signal is the laboratory's reference point of (+) or (-.

Answered 11/1/2015

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Exposure, not infect: A positive antibody result against hepatitis c with a high scr most likely represents a true prior exposure to hcv. However, even people with high antibody responses can spontaneously clear the hcv infection. So, everybody with a positive hcv antibody has to get an hcv RNA (viral load) checked to see if they have active infection. Only people with virus are infectious and may need treatment.

Answered 9/17/2016

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