Unknown: It is best to take synthroid (thyroxine) by itself on an empty stomach and wait at least 40 min before eating. Taking supplements at the same time can affect the absorption of synthroid (thyroxine). I can find no studies that have examined green coffee extract on thyroid hormone absorption. If thyroid levels change while taking the extract it means that it is probably affecting the absorption.
Answered 3/8/2013
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