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A member asked:
Why do ssri's cause pupil dialation?
A doctor has provided 1 answer
Serotonin effect: Ssris increase serotonin levels in nerves throughout the body, including the eye. Excess serotonin acting on the 5-ht7 and 5-ht2a/2c receptors in the eye produce relaxation of the pupil and passive dilation. This effect is countered by the 5-ht1a receptor which contracts the muscle. However, when both receptors are simultaneously stimulated, the predominant effect is mydriasis (dilation).
Answered 3/29/2018
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