Does digeorge syndrome affect your appearance?

Possibly: Since this process involves more than one defect, not all will show the same features. Most are mild & could be picked up by those knowledgeable of syndrome variations but may not be apparent to the public.

Possibly: Per Mayo Clinic DiGeorge facial features may include “small, low-set ears, short width of eye openings (palpebral fissures), hooded eyes, a relatively long face, an enlarged nose tip (bulbous), or a short or flattened groove in the upper lip.” cleft palate w or w/o cleft lip can occur. As stated by Dr. Ferguson - there can be minor or marked difference.