Sir, i have no symptoms of neurofibromatosis and also not in my father and mom but some lumps are in my hand and very few on my thigh, is it lipoma?

Possibly: Lipoma is a benign tumor which is the most common cause of lumps under the skin. It has a very typical physical exam and your family doctor should be able to tell you after examining the area whether it is or not.

Can not know: Lumps come in multitude of varieties in size, texture, firmness, and color. The best determination if concerned is to consult physician perhaps dermatologist for examination and if necessary testing.