what is the definition or description of: chronic lymphocytic leukemia ivgh?

Question

What sort of disease is chronic lymphocytic leukemia (c.L.L.)?

Answer 1

CLL IgVH: Immunoglobulin variable region (igvh) mutation status is an important marker for prognosis in patients with cll. Testing is by polymerase chain reaction (pcr) amplification of the igvh region, followed by dna sequencing. Ref: http://www.Mayomedicallaboratories.Com/articles/hottopics/transcripts/2008/2008-11b-cli-pt-2/11b-26.Html.

Answer 2

A test 2 assess risk: The correct name is igvh mutational status assay. This is a gene test performed only on leukemic cells of patients with cll to assess risk of progression, and death from cll. The readout is either mutated (which is favorable) or unmutated (unfavorable). Igvh mutations happen during the normal generation of antibodies in white cells.

Answer 3

Lymph system cancer: Lymphocytes are normal cells of the immune system that protects the body from infection. When these cells become cancerous, they grow out of control in the bone marrow, blood and other organs. All is very common in children but can occur in adults. With children, it is truly one of our success stories thanks to clinical trials with cure rates above 90%. Adults do not do as well.

Answer 4

Cancer: Type of leukemia that affects lymphoid cells, bone marrow.

Answer 5

Blood cancer: All is a form of leukemia which in turn is a form of cancer, more specifically blood and bone marrow cancer. The word "acute" means it progresses faster, as opposed to chronic cases that usually have a slower progression. The word "lymphoblastic" means immature lymphoid and describes the type of malignant cell involved in this leukemia, as opposed to other types of cells, for example myeloid.

Answer 6

ALL: ALL is a type of leukemia that starts from white blood cells in the bone marrow, the soft inner part of bones. It develops from cells called lymphocytes, a type of white blood cell central to the immune system, or from lymphoblasts, an immature type of lymphocyte. ALL invades the blood and can spread throughout the body to other organs, such as the liver, spleen, and lymph nodes

Answer 7

Yes: Advanced leukemia of any sort (aml, all, cml, cll) can lead to anemia. However, early leukemia (rai 0 cll) may not result in anemia.

Answer 8

Yes: May occur, but is not absolute.

Answer 9

Different cells: Emia = blood. An-emia = lack of red blood cells (low hgb) associated with fatigue leukocytosis = more white blood cells (WBC) in the blood. One cause of leukocytosis is an increase in WBC cancer cell called leukemia.

Answer 10

A sign vs a disease: Anemia refers to a low red blood cell count and diminished capacity to carry oxygen. This has many causes. Leukemia is a cancer- a type of white blood cell growing out of control and preventing the others from doing their normal work.

Answer 11

Yes: Depending on the type of leukemia, this is possible. For example, chronic lymphocytic leukemia is a slowly prgressive disease and it may take a while before the marrow becomes significantly involved to the point of affecting the red blood cells. Also, in the early stages of leukemia, anemia may not be present.

Answer 12

Yes. : It depends upon the rate of leukemia progression. If a leukemia developed rapidly, red cell mass may fall very little during that time, as the half life of a red cell is 100-120 days. Leukemias that evolve more slowly are more likely to have associated anemia, sometimes very severe. While not always true, slowly evolving leukemias often have a better prognosis because of their indolent nature.

Answer 13

Possibly: There are a lot of reasons for leukopenia. Usually isolated low white cells is not a sign of leukemia if the red blood cells and the platelets also found in blood are fine. Leukopenia develops in leukemia because all the bone marrow cells that eventually end up in the blood stream are crowded out by leukemia cells.

Answer 14

See below: Leukopenia is a decrease in the white blood cell (WBC) count. It does not lead to leukemia but can be a manifestatiin of leukemia even though leukemia is usually associated with high wbc.

what is the definition or description of: chronic lymphocytic leukemia ivgh?

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