A member asked:

Is wilm's tumor hereditary?

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Dr. George Chiang answered

Specializes in Pediatric Urology

Yes: It can be. There are certain syndromes (beckwith-wiedeman, wagr, and denys-drash) that are associated with a genetic abnormality that causes wilms tumor. The direct hereditary risk is slightly higher but not clea.R.

Answered 11/17/2014

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In some cases: While wilms' tumor usually occurs sporadically, there are common genes/gene mutations that have been discovered in patients with wilms' tumor. There is also increased incidence in association with certain conditions, such as hemihypertrophy and beckwith-wideman syndrome (omphalocele, macroglossia, organomegaly). This suggests a genetic link in some patients.

Answered 6/29/2013

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Not really: Wilms tumor is a childhood cancer of the kidneys. It usually occurrs sporadically. However in some cases when it involves a syndrome like beckwith-weidemann it can be hereditary.

Answered 10/22/2012

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