Are hie and autism related?

No: There is no strong scientific data that links the two conditions, although there have been cases studies that suggested the incidence of autism was higher in children who suffered moderate to severe perinatal hie.

Ummm, not really. : Hie or hypoxia-ischemic encephalopathy is causative in many behavioral and learning disorders in children, adolescents, and adults. Autism is the result of a confluence of genetic predisposition and neurotoxicity. So someone with perfectly typical genetic endowment can have hie, while a much more minimal cortical insult could make autism penetrate.