A member asked:

What is the genome for idiopathic hypertrophic subaortic stenosis?

2 doctors weighed in across 2 answers

Autosomal Dominant: Ihss is caused by mutations in sarcomere genes and is the most common monogenic cardiovascular disorder.

Answered 5/15/2013

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Dr. J Roberts answered

Autosomal Dom.: Many genes code for this anomaly of sarcomere proteins: chr 14 in the beta-myosin heavy chain; protein c cardiac myosin. This error creates some degree of left ventricular hypertrophy involving the septum between the ventricles: asymmetric septal hypertrophy. Lethal arrhythmias may occur. Genetic testing is available. Seek opinion of a cardiologist.

Answered 7/7/2014

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