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A member asked:
How does coronary artery disease develop in the body?
4 doctors weighed in across 2 answers
Slowly: Low density lipoprotein (ldl) is taken up by endothelial cells in blood vessels. The LDL is broken down (oxidized) and absorbed by macrophages within the wall of the blood vessel. Ultimately, the macrophage which is full of oxidized LDL will die. The dead cells and cholesterol accumulate in the wall of the artery interfering with the flow of blood.
Answered 7/26/2018
6.3k views
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CAD: High blood pressure, high cholesterol, sedentary life, smoking, genetics.
Answered 3/24/2020
5.4k views
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